Which of the following is a potential consequence of using barbiturates?

Barbiturates are central nervous system depressants that have sedative and hypnotic effects. One of the major risks associated with their use is the potential for overdose. Barbiturates can significantly depress the respiratory system and lower blood pressure, which can lead to life-threatening situations such as respiratory failure or coma, especially when taken in excessive doses or combined with other depressants like alcohol.

Because of their narrow therapeutic window, the difference between a therapeutic and a toxic dose can be quite small, making the risk of overdose particularly concerning. This characteristic is one of the primary reasons why the clinical use of barbiturates has declined in favor of safer alternatives for managing conditions like anxiety and sleep disorders. Understanding the risks associated with barbiturate use is critical for safe medical practice and patient education.