Which of the following is an example of a nonbenzodiazepine?

Zolpidem tartrate represents a nonbenzodiazepine medication primarily used for the short-term management of insomnia. This compound falls under the category known as Z-drugs, which are chemically distinct from benzodiazepines but share similar mechanisms of action, specifically targeting GABA receptors to facilitate sleep induction. Zolpidem is characterized by a rapid onset of action and a relatively short duration of effect, making it suitable for patients seeking immediate relief from sleep disturbances without the extended sedation often associated with longer-acting sedatives.

In contrast, the other options listed are all benzodiazepines. Lorazepam, clonazepam, and flurazepam belong to this class, which is known for its anxiolytic, sedative, and muscle relaxant properties. These medications work by enhancing the effect of GABA, but they often have longer half-lives and come with a risk of dependency and withdrawal symptoms when used over extended periods. Therefore, the distinctive profile of zolpidem tartrate as a nonbenzodiazepine makes it an important option in the management of insomnia, differentiating it from the benzodiazepine medications mentioned.