Which benzodiazepine is noted for not delaying REM sleep?

Temazepam is known for its unique pharmacological profile among benzodiazepines, particularly its effect on sleep architecture. Unlike many other benzodiazepines, which can suppress REM (Rapid Eye Movement) sleep due to their hypnotic properties, temazepam tends to preserve REM sleep. This is significant because REM sleep is an essential component of a healthy sleep cycle, associated with memory consolidation and emotional regulation.

Temazepam primarily acts as a sedative-hypnotic medication, commonly prescribed for insomnia. It facilitates sleep onset and maintenance while having a relatively sparing effect on REM sleep. This characteristic makes it preferable for patients who require sleep medication without the risk of REM sleep disturbance, which can lead to negative consequences like impaired cognitive function and mood disturbances.

Other benzodiazepines, such as diazepam, alprazolam, and lorazepam, are more likely to reduce REM sleep during their use. Therefore, temazepam stands out as the optimal choice for preserving REM sleep while providing effective treatment for insomnia.