What is the therapeutic range for phenytoin in treating seizures?

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The therapeutic range for phenytoin in the management of seizures is indeed 10-20 mcg/mL. This range is critical for maintaining effective seizure control while minimizing the risk of toxicity. Phenytoin is a commonly used antiepileptic drug, and its levels must be monitored due to its nonlinear kinetics and the potential for significant adverse effects if the levels rise above the therapeutic range.

Maintaining phenytoin levels within this range ensures that sufficient medication is present to exert its anticonvulsant effects without reaching levels that could lead to side effects such as ataxia, nystagmus, or more severe reactions like cardiovascular issues. Therefore, the choice indicating a therapeutic range of 10-20 mcg/mL reflects standard clinical practice aimed at optimizing patient outcomes in seizure management.

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