What class of antipsychotics does not have significant side effects common to older antipsychotics?

Atypical antipsychotics are known for having a more favorable side effect profile compared to older, typical antipsychotics. The distinction lies primarily in their mechanisms of action and the neurotransmitter systems they target. Atypical antipsychotics often affect both dopamine and serotonin receptors, which can result in a reduction of the extrapyramidal side effects (EPS) commonly associated with typical antipsychotics. These side effects can include tremors, rigidity, and bradykinesia, which are manifestations of movement disorders.

In contrast, typical antipsychotics primarily block dopamine receptors and are associated with a higher incidence of EPS, leading to a greater burden of side effects. Moreover, atypical antipsychotics also tend to have a lower risk of tardive dyskinesia, a long-term movement disorder linked to prolonged use of typical antipsychotics.

The other options, such as full agonists and partial agonists, are not relevant classifications for antipsychotics in the context of comparing side effects. Full agonists and partial agonists are terms generally used to describe the action of drugs at certain receptors but do not specifically encompass the broader category of antipsychotic medications, especially with respect to their clinical